Born from a chance discovery, Mercaptor is dedicated to reshaping neurology through innovation and compassion, turning scientific uncertainty into a driving force for a future where neurology shines as a robust pillar in medicine.
Captons set themselves apart from other CNS therapeutics. As small-molecule drugs, Captons rely on sulfonic acid functional groups for their biological activity. They are pharmacokinetically enabled and pharmacodynamically disabled by substituting the sulfonate for a thiol.
Thiol substitution for sulfonate enhances the drug’s ability to traverse the blood-brain barrier (BBB). In the presence of elevated levels of both redox-active transition metal ions and reactive oxygen species (ROS), the Captons’ thiol can be oxidized back to the biologically active sulfonate.
Elevated concentrations of free metals and ROS in tissues, combined with the absence of blood albumin, create a unique environment exclusive to areas of the brain subjected to insult or injury—not in healthy brain tissue or the periphery.
Guided by the behavior of Captons, therapeutic activity is elicited at doses and locations determined through dynamic interactions with the targeted neuropathology.
Avoiding the false comfort of certainty, honest scientists sometimes catch a glimpse into the infinite Universe.
These rare insights are more likely to help move the world forward than countless years spent trying to prove expectations. The opportunity obliges us to take responsibility for the continued development of what we have learned.
New Technology Addresses Brain Trauma Including Alzheimer’s, TBI, and Epilepsy SAN FRANCISCO, Jan. 5, 2024 /PRNewswire-PRWeb/ — Mercaptor Inc, a privately held pharmaceutical company, today announced a breakthrough
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